Tuesday, July 24, 2012

Credit Watch on the Rhine | Poems by Dr. Goose: Finance and ...

  • Said a Harvard professor of econ, "That Google's got something unique on: They have cash by the score, Yet still borrow more; This is so...

  • Facebook is valued at plenty By Wall Street's high-tech cognoscenti, Based on 1 billion friends Times $5 each, then Times the IPO mu...

  • In the IPO pricing of LinkedIn, Which doubled before one had blinked in, Either banks ripped off clients, Or it's more art than science; ...

  • Said a Goldmanite, freaking his guys out: "How my conscience courageously cries out! Though I trusted this firm, it Exploited poor Kermit...

  • Thomas Hoenig, the hawkish Fed governor, Says: "The Dollar has way too much dove in 'er; With a null target rate, I doubt we'll deflate,...

  • A maid whose hotel greatly trusted her Once confronted a sight that disgusted her, And beat a retreat From a luxury suite, When an IMF p...

  • Said Krugman, with skeptical wince: "Employment just doesn't convince; Though it tumbled off greatly In 2008, we Have seen no recovery s...

  • Said Mankiw: "I've made a regression Of the Fed funds rate setting progression, Which suggests we may snap Our liquidity trap, Or at ...

  • America's unequal strata, As confirmed by definitive data, Have made it quite plain, On Wall Street and Main, That something is deeply t...

  • Said an equity trader, "I'll cop to this: I can't tell why we tanked from the top to this, But the punters of punts All concluded at onc...

  • Source: http://www.limericksecon.com/2012/07/credit-watch-on-rhine.html

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    Nexus Q starts shipping in earnest from Google Play, social streaming reaches our doors in five days

    Nexus Q review - cables

    The Nexus Q media streamer might not have generated the same kind of mania as the Nexus 7 tablet, but it's still good news that Google is now shipping its mysteriously social orb. Google Play has the Q in stock and expects new US orders to arrive on doorsteps within the next three to five days. We're not expecting the kind of runaway sales of the $299 hub that have made the more utilitarian Nexus 7 hard to find, but anyone who spends a lot of their leisure time in the Google media ecosystem might appreciate the integration. Alas, that made-in-the-USA design still isn't available outside of the USA, so those in other countries will have to make do with alternatives.

    Filed under:

    Nexus Q starts shipping in earnest from Google Play, social streaming reaches our doors in five days originally appeared on Engadget on Tue, 24 Jul 2012 18:10:00 EDT. Please see our terms for use of feeds.

    Permalink Phandroid  |  sourceGoogle Play  | Email this | Comments

    Source: http://www.engadget.com/2012/07/24/nexus-q-starts-shipping-in-earnest-from-google-play/

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    Saturday, July 21, 2012

    Injury Law Firm in Los Angeles | Personal Injury News, Lawyers ...

    A personal injury is an injury to an individual?s body, or mind and is the most common type of legal claim. ?Injury law handles the physical harm a person has suffered or endured due to another person?s negligent actions, or failure to act. ?This suffering can be both physical and emotional. ?An experienced personal injury attorney helps personal injury victims recover the proper compensation for a full recovery. ?The more serious a personal injury is the more likely it is that the victim will recover higher compensation. ?Some of the most common types of personal injury cases include but are not limited too:

    • Brain Injuries
    • Truck Accidents
    • Car Accidents
    • Motorcycle Accidents
    • Burn Injuries
    • Slip and Fall Accidents
    • Construction Accidents
    • Bicycle Accidents

    Estey & Bomberger, LLP is a Los Angeles personal injury law firm with some of the best and most experienced injury attorneys in the entire state of California. ?The California personal injury attorneys at Estey & Bomberger, LLP have over 40 years of combined experience practicing injury law and have successfully handled hundreds of injury cases. ?These injury attorneys offer all victims of personal injuries free legal consultations and work on a contingency-fee basis.

    Source: http://personalinjurylawyers360.com/injury-law-firm-in-los-angeles/

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    Source: http://griffiesstvilma88.typepad.com/blog/2012/07/injury-law-firm-in-los-angeles-personal-injury-news-lawyers.html

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    Fla. consumer advocate urges health care action

    [ [ [['Connery is an experienced stuntman', 2]], 'http://yhoo.it/KeQd0p', '[Slideshow: See photos taken on the way down]', ' ', '630', ' ', ' ', ], [ [['Connery is an experienced stuntman', 7]], ' http://yhoo.it/KpUoHO', '[Slideshow: Death-defying daredevils]', ' ', '630', ' ', ' ', ], [ [['know that we have confidence in', 3]], 'http://yhoo.it/LqYjAX ', '[Related: The Secret Service guide to Cartagena]', ' ', '630', ' ', ' ', ], [ [['We picked up this other dog and', 5]], 'http://yhoo.it/JUSxvi', '[Related: 8 common dog fears, how to calm them]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 5]], 'http://bit.ly/JnoJYN', '[Related: Did WH share raid details with filmmakers?]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 3]], 'http://bit.ly/KoKiqJ', '[Factbox: AQAP, al-Qaeda in Yemen]', ' ', '630', ' ', ' ', ], [ [['have my contacts on or glasses', 3]], 'http://abcn.ws/KTE5AZ', '[Related: Should the murder charge be dropped?]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 5]], 'http://yhoo.it/JD7nlD', '[Related: Bristol Palin reality show debuts June 19]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 1]], 'http://bit.ly/JRPFRO', '[Related: McCain adviser who vetted Palin weighs in on VP race]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['the 28-year-old neighborhood watchman who shot and killed', 15]], 'http://news.yahoo.com/photos/white-house-stays-out-of-teen-s-killing-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120411/martinzimmermen.jpg', '630', ' ', 'AP', ], [ [['He was in shock and still strapped to his seat', 6]], 'http://news.yahoo.com/photos/navy-jet-crashes-in-virginia-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120406/jet_ap.jpg', '630', ' ', 'AP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]

    [ [ [['did not go as far his colleague', 8]], '29438204', '0' ], [ [[' the 28-year-old neighborhood watchman who shot and killed', 4]], '28924649', '0' ], [ [['because I know God protects me', 14], ['Brian Snow was at a nearby credit union', 5]], '28811216', '0' ], [ [['The state news agency RIA-Novosti quoted Rosaviatsiya', 6]], '28805461', '0' ], [ [['measure all but certain to fail in the face of bipartisan', 4]], '28771014', '0' ], [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]

    Source: http://news.yahoo.com/fla-consumer-advocate-urges-health-care-action-150221929--finance.html

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    Wednesday, July 18, 2012

    High-security handcuffs unlocked with 3D-printed key

    Jacob Aron, technology reporter

    a0035-000104.jpg(Image: Steven Puetzer/Getty)

    High-security police handcuffs can be opened with keys fashioned by a 3D printer, potentially giving criminals an easy way out of incarceration.

    Unlike the lock on your front door, handcuffs don't use individually patterned keys, so their security relies on handcuff manufacturers limiting the commercial availability of keys. Now, a German security researcher, who goes only by the name "Ray" and previously advised the German police on handcuff technology, has found a high-tech loophole - print your own.

    Speaking at the Hackers on Planet Earth conference in New York, Ray said he acquired a key for UK firm Chubb's handcuffs from eBay, where they occasionally appear for sale, and got hold of a German Bonowi key from an unnamed source. He measured them with callipers and created a 3D computer model with the exact dimensions for each key, which he then reproduced using both a laser cutter and a 3D printer. He also tried to duplicate the keys of a third company, the German Clejuso, but found the plastic key wasn't strong enough to open the handcuffs.

    Ray now plans to upload the Chubb key to Thingiverse, a 3D-printing repository, but says he won't share the Bonowi or Clejuso key as they are harder to obtain. It probably won't be long until the keys reach controversial file-sharing site The Pirate Bay, which earlier this year announced its intentions to offer "physible" downloads that can be 3D printed. Ray denies the 3D files will make it easier for criminals to escape, however. "If someone is planning a prison or court escape, he can do it without our help," he said. "We're just making everyone aware, both the hackers and the police."


    Subscribe to New Scientist Magazine

    Source: http://feeds.newscientist.com/c/749/f/10897/s/21776b47/l/0L0Snewscientist0N0Cblogs0Conepercent0C20A120C0A70Chigh0Esecurity0Ehandcuffs0Eunlock0Bhtml0DDCMP0FOTC0Erss0Gnsref0Fonline0Enews/story01.htm

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    Tuesday, July 17, 2012

    News and Society -Crime News Blog: Self Defense: Powerful New ...

    ByDave Artman

    Batteries were invented in the late 1800's. Shortly thereafter an inventor by the name of John Burton from Wichita, Kansas received a patent for his "electric prod pole." He developed this as a way to direct his cattle without damaging their hides.

    That was the beginning of the stun gun industry. As is often the case, the military were the first to see the potential for this new device as a nonlethal weapon. Stun devices are the second most popular personal defense product used for self-defense. Because they are so effective and sleek-looking, women love them for female self-defense.

    Innovations and new products in the stun gun industry are happening all the time. Here are four new models of new stun guns that customers will love for self-defense as a personal defense product.

    The first one is called the iStun smart phone. It is 3.8 million volts in a package that looks like a smart phone. It has the safety switch that prevents accidental discharge and a built-in LED flashlight. It is completely rechargeable and includes a premium leather case, charging cord and, since it's a "Guard Dog" product, a free 18% solution pepper spray canister.

    The second one is even more powerful-the Streetwise brand "Blackout" stun gun that's four million volts in one of the smallest packages you can find. It is only 3.25 inches tall and 1.81 inches wide. It also is completely rechargeable and comes with a lifetime manufacturers warranty and a free durable holster.

    Third on our list of new stun guns is one that looks like a Cell Phone. It is 4.5 inches tall, 2 inches wide, less than an inch thick and is 3.8 million volts in a package.. It also is completely rechargeable and has a built-in LED flashlight. It comes with a charging cord and premium flip top leather carrying case. It also has a free 18% pepper spray canister included.

    And last on the list is the Zap brand "Enforcer" stun gun flashlight. It is 2,000,000 volts and unlike any other stun flashlight on the market, it has a real-time display that shows the remaining run time and remaining number of shocks. It comes in an aluminum body and includes a rechargeable battery, wall charger, wrist strap and belt clip holster. The flashlight is 110 lumens. This is a perfect product to carry in your car for self-defense.

    Check out our huge selection of Stun Guns. They are inexpensive and on average 90% effective.

    The Home Security Superstore is one of the oldest and largest independent distributors of high quality home security, surveillance, spy, self-defense, survival and safety products. We carry a wide range of self-defense products including tasers, stun guns, pepper sprays and other nonlethal weapons that can save your life in the event of an attack.

    Article Source:http://EzineArticles.com/?expert

    Source: http://newsandsociety-crimenews.blogspot.com/2012/07/self-defense-powerful-new-stun-guns.html

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    Pregnant Kentucky woman grieves loss of family after fatal crash ...

    A young pregnant woman from Louisville is now grief-stricken after a car accident killed three of her immediate family members. The woman is five months pregnant, so her father asked that she stay behind while the rest of her family went on vacation, which involved some hiking that might have been dangerous for the mother-to-be. However, a deadly car accident occurred on the family's return trip home, and now the woman has lost her 38-year-old father, 31-year-old stepmother and 15-year-old sister due to the crash.

    The family was traveling on Interstate 75 when their SUV was clipped by a truck, causing the family's vehicle to flip over. The stepmother and younger sister died at the scene, and the father died later in the hospital.

    The pregnant woman had almost gone on the trip herself, but her father insisted that she stay home because of her pregnancy. She is still trying to cope with the fact that her family is gone, and she now wears a bracelet that has her sister's name on it.

    As she tries to understand the depth of her immeasurable loss, this young woman must also deal with the cost of funerals and any medical treatment her father may have received. It was unclear whether police filed any charges against the driver of the other vehicle, but taking a close look at the accident report will help the young woman determine whether civil actions are in order. If negligent driving is shown to be a factor in the crash, she may have grounds to seek compensation under Kentucky's wrongful death laws.

    Source: wdrb.com, "Fatal crash kills 3 members of Louisville family," Bennett Haeberle, July 9, 2012

    Source: http://www.eastkentuckyinjurylawyer.com/2012/07/pregnant-kentucky-woman-grieves-loss-of-family-after-fatal-crash.shtml

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    Sunday, July 15, 2012

    Obama: DC 'feels as broken as it did 4 years ago'

    President Barack Obama campaigns despite the pouring rain at the historic Walkerton Tavern & Gardens in Glen Allen, Va., near Richmond, Saturday, July 14, 2012. It is in the Congressional district represented by Republican House Majority Leader Eric Cantor, R-Va., a key county in a crucial swing state of the presidential election. (AP Photo/J. Scott Applewhite)

    President Barack Obama campaigns despite the pouring rain at the historic Walkerton Tavern & Gardens in Glen Allen, Va., near Richmond, Saturday, July 14, 2012. It is in the Congressional district represented by Republican House Majority Leader Eric Cantor, R-Va., a key county in a crucial swing state of the presidential election. (AP Photo/J. Scott Applewhite)

    President Barack Obama holds a re-election campaign rally despite the heavy rain at the historic Walkerton Tavern & Gardens in Glen Allen, Va., near Richmond Saturday, July 14, 2012. It is in the Congressional district represented by House Majority Leader Eric Cantor, R-Va., a key county in a crucial swing state of the presidential election. (AP Photo/J. Scott Applewhite)

    (AP) ? President Barack Obama says Washington "feels as broken as it did four years ago," when he took office.

    He says he's most frustrated by the inability "to change the atmosphere" in the nation's capital "to reflect the decency and common sense of ordinary people" who want their leaders to solve problems.

    "There's enough blame to go around for that," he told CBS' "Sunday Morning."

    CBS' Charlie Rose interviewed the president and first lady Michelle Obama at the White House on Thursday and has aired parts of the conversation on different network shows since then.

    Reflecting on more than 3 ? years in office, Obama said, "I think there's no doubt that I underestimated the degree to which in this town politics trump problem solving."

    On a lighter note, he said the White House will be a quieter place this summer because his daughters, 11-year-old Sasha and 14-year-old Malia, will be in sleep-away camp for a month. The president, meanwhile, will be campaigning for re-election, spending lots of time outside Washington.

    "We're going to be experiencing the first stages of-empty nest syndrome," he said. Asked if he's prepared for that, the president said, "Well, I get a little depressed."

    The first lady said the Obamas will find a way for "family time, because any time the girls are out of school, that's important time for us to spend as a family. We're still parents where you have to juggle your time around when they're free and summer time is that time."

    In a separate interview, taped Friday and released Sunday, the 50-year-old president said the food and unfamiliar mattresses are downsides of the campaign trail.

    "When you're on the road, you end up eating a lot of stuff that tastes really good at the time but later on in the day can catch up with you, and I'm now getting to the age where being in my own bed as opposed to some other bed, is not always great for my back," he told WJLA-TV in Washington.

    Obama also revealed, when asked what voters don't know about him, that he "can cook a really mean chili," though his wife will claim that "I haven't cooked it for about 10 years, so I really shouldn't get too much credit for it."

    And one more: "I'm a surprisingly good pool player, so if you ever see me in a pool hall, don't just think that you can ..."

    "Don't walk up and throw down money is what you're saying?" interviewer Scott Thurman asked.

    "That's what I'm saying," the president said. "I might end up cleaning your clock. That's a possibility."

    The president also described himself as "a pretty good doodler" of faces, people and other things.

    "Sometimes when I'm in a big important international meeting and you see me writings stuff down it might be that I'm just drawing some folks," he said.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2012-07-15-Obama/id-81768ad07fa84f139229625692edb31b

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    Saturday, July 14, 2012

    Canon LV-8320


    As a rule, video projectors are best at projecting movies and other video content, while data projectors excel at displaying PowerPoint and other business presentations. The Canon LV-8320 ($999 direct) bends that rule. This business projector did a decent job on our data image tests, but had surprisingly good video quality. Its audio isn't up to what you'd get with an entertainment projector, but the LV-8320 ?is definitely worth considering if your business or classroom presentations have substantial video content.?

    The LV-8320 is an LCD-based projector. It has a rated brightness of 3,000 lumens, and a native WXGA (1,280 by 800) resolution, at a 16:10 aspect ratio compatible with many laptops.?

    The LV-8320 is silver colored, with rounded corners. At the lens are focus and zoom (1.6x) rings. At 3.8 by 13.7 by 10.9 inches (HWD) and 7.5 pounds, this projector is portable, though a little larger than you may want to carry around regularly. It does come with a soft carrying case.?

    It has a standard selection of ports for today's data projectors; Ethernet; 2 VGA-in (one of which doubles as component video); RS232; 2 audio-in jacks (one of which can serve as a mic jack) and an audio-out; video ports also include component, S-Video, plus an HDMI port, which last year's Canon LV-8225 ($799 direct, 4 stars) lacked. The LV-8225 is slightly smaller and lighter than the LV-8320, weighing in at 6.6 pounds.?

    Testing

    Data image quality, tested using the DisplayMate suite, was suitable for most business and classroom uses. Text was of average readability. Most colors seemed reasonably true, although one issue that I came across was tinting. Bright areas sometimes showed a slight yellow tint, and light grays often had a greenish tint that at worst was significant enough to be distracting. It was less prominent in High Contrast mode than in Standard or Presentation modes, but still visible. I'd hesitate to use this projector in situations where exacting color is paramount.?

    Video was a pleasant surprise, better than average for a data projector, good enough to show lengthy clips as part of a presentation. You could even use it for movies, although you'd best sit close to the projector or use an external sound system as the audio from the one 10W speaker is on the faint side and not of particularly good quality.?

    As an LCD projector, it's blessedly immune from the distracting rainbow effect that plagues many DLP projectors. Also, its lamp is relatively long-lasting when used in Quiet (aka Eco) mode, rated at 5,000 hours; in Standard mode it's a more typical 3,000 hours. Still, its bulb life pales in comparison with Casio projectors using that company's hybrid LED/laser light source, such as the Casio Slim XJ-A246 ($1,499 direct, 3.5 stars)?their LED lamps are designed to last up to 20,000 hours.?

    The Canon LV-8320 is priced a little on the high side for a data projector of its capabilities. For about the same money, you could get a high-quality short-throw WXGA projector, such as the Optoma TW610ST ($1,000 street, 4 stars) or the NEC Display Solutions NP-M300WS ($1,099 direct, 4 stars)?both Editors' Choice models?that lets you project an image from very close to the screen.?

    For a little more money, the Editors' Choice Epson PowerLite 1775W Multimedia Projector ($1,199 direct, 4 stars)?a long-throw model?is much lighter than the LV-8320 and offers WiFi connectivity plus the ability to run presentations off of a USB thumb drive. The Epson showed excellent data and good video image quality in our testing, and had better than expected sound quality as well.?

    The LV-8320 is a likeable projector, with surprisingly good video quality for a data projector. I'd like it a bit better, though, if its data images were more consistently tint-free.

    ?More projector reviews:

    ??? Canon LV-8320
    ??? Epson MegaPlex MG-50 Projector
    ??? Casio Short Throw XJ-ST155
    ??? Casio Slim XJ-A246
    ??? 3M Mobile Projector MP410
    ?? more

    Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/4KFh4gFqRuQ/0,2817,2406999,00.asp

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    Friday, July 6, 2012

    Techclap.com: TechClap.com Covers Latest Technology News ...

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    Source: http://seovalidator.net/techclap.com

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    Electorate sees campaign as exhausting but informative (Washington Bureau)

    Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS and RSS Feed via Feedzilla.

    Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/237281140?client_source=feed&format=rss

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    UCLA bioengineers discover single cancer cell can produce up to 5 daughter cells

    UCLA bioengineers discover single cancer cell can produce up to 5 daughter cells [ Back to EurekAlert! ] Public release date: 5-Jul-2012
    [ | E-mail | Share Share ]

    Contact: Matthew Chin
    mchin@support.ucla.edu
    310-206-0680
    University of California - Los Angeles

    Findings could aid researchers in understanding progression of disease

    It's well known in conventional biology that during the process of mammalian cell division, or mitosis, a mother cell divides equally into two daughter cells. But when it comes to cancer, say UCLA researchers, mother cells may be far more prolific.

    Bioengineers at the UCLA Henry Samueli School of Engineering and Applied Science developed a platform to mechanically confine cells, simulating the in vivo three-dimensional environments in which they divide, and found that, upon confinement, cancer cells often split into three or more daughter cells.

    "We hope that this platform will allow us to better understand how the 3-D mechanical environment may play a role in the progression of a benign tumor into a malignant tumor that kills," said Dino Di Carlo, an associate professor of bioengineering at UCLA and principal investigator on the research.

    The biological process of mitosis is tightly regulated by specific biochemical checkpoints to ensure that each daughter cell receives an equal set of sub-cellular materials, such as chromosomes or organelles, to create new cells properly.

    However, when these checkpoints are miscued, the mistakes can have detrimental consequences. One key component is chromosomal count: When a new cell acquires extra chromosomes or loses chromosomes known as aneuploidy the regulation of important biological processes can be disrupted, a key characteristic of many invasive cancers. A cell that divides into more than two daughter cells undergoes a complex choreography of chromosomal motion that can result in aneuploidy.

    By investigating the contributing factors that lead to mismanagement during the process of chromosome segregation, scientists may better understand the progression of cancer, said the researchers, whose findings were recently published online in the peer-reviewed journal PLoS ONE.

    For the study, the UCLA team created a microfluidic platform to mechanically confine cancer cells to study the effects of 3-D microenvironments on mitosis events. The platform allowed for high-resolution, single-cell microscopic observations as the cells grew and divided. This platform, the researchers said, enabled them to better mimic the in vivo conditions of a tumor's space-constrained growth in 3-D environments in contrast to traditionally used culture flasks.

    Surprisingly, the team observed that such confinement resulted in the abnormal division of a single cancer cell into three or four daughter cells at a much higher rate than typical. And a few times, they observed a single cell splitting into five daughter cells during a single division event, likely leading to aneuploid daughter cells.

    "Even though cancer can arise from a set of precise mutations, the majority of malignant tumors possess aneuploid cells, and the reason for this is still an open question," said Di Carlo, who is also a member of the California NanoSystems Institute at UCLA. "Our new microfluidic platform offers a more reliable way for researchers to study how the unique tumor environment may contribute to aneuploidy."

    ###

    Other authors on the paper included Henry Tat Kwong Tse and Westbrook McConnell Weaver, both UCLA biomedical engineering graduate students. The research team is currently seeking to partner with cancer researchers to further investigate the importance of confined environments on the development of cancer.

    The study was funded by the UCLA Henry Samueli School of Engineering and Applied Science.

    For more on the Di Carlo laboratory's research, visit www.biomicrofluidics.com.

    The UCLA Henry Samueli School of Engineering and Applied Science, established in 1945, offers 28 academic and professional degree programs and has an enrollment of more than 5,000 students. The school's distinguished faculty are leading research to address many of the critical challenges of the 21st century, including renewable energy, clean water, health care, wireless sensing and networking, and cybersecurity. Ranked among the top 10 engineering schools at public universities nationwide, the school is home to nine multimillion-dollar interdisciplinary research centers in wireless sensor systems, wireless health, nanoelectronics, nanomedicine, renewable energy, customized computing, the smart grid, and the Internet, all funded by federal and private agencies and individual donors.


    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


    UCLA bioengineers discover single cancer cell can produce up to 5 daughter cells [ Back to EurekAlert! ] Public release date: 5-Jul-2012
    [ | E-mail | Share Share ]

    Contact: Matthew Chin
    mchin@support.ucla.edu
    310-206-0680
    University of California - Los Angeles

    Findings could aid researchers in understanding progression of disease

    It's well known in conventional biology that during the process of mammalian cell division, or mitosis, a mother cell divides equally into two daughter cells. But when it comes to cancer, say UCLA researchers, mother cells may be far more prolific.

    Bioengineers at the UCLA Henry Samueli School of Engineering and Applied Science developed a platform to mechanically confine cells, simulating the in vivo three-dimensional environments in which they divide, and found that, upon confinement, cancer cells often split into three or more daughter cells.

    "We hope that this platform will allow us to better understand how the 3-D mechanical environment may play a role in the progression of a benign tumor into a malignant tumor that kills," said Dino Di Carlo, an associate professor of bioengineering at UCLA and principal investigator on the research.

    The biological process of mitosis is tightly regulated by specific biochemical checkpoints to ensure that each daughter cell receives an equal set of sub-cellular materials, such as chromosomes or organelles, to create new cells properly.

    However, when these checkpoints are miscued, the mistakes can have detrimental consequences. One key component is chromosomal count: When a new cell acquires extra chromosomes or loses chromosomes known as aneuploidy the regulation of important biological processes can be disrupted, a key characteristic of many invasive cancers. A cell that divides into more than two daughter cells undergoes a complex choreography of chromosomal motion that can result in aneuploidy.

    By investigating the contributing factors that lead to mismanagement during the process of chromosome segregation, scientists may better understand the progression of cancer, said the researchers, whose findings were recently published online in the peer-reviewed journal PLoS ONE.

    For the study, the UCLA team created a microfluidic platform to mechanically confine cancer cells to study the effects of 3-D microenvironments on mitosis events. The platform allowed for high-resolution, single-cell microscopic observations as the cells grew and divided. This platform, the researchers said, enabled them to better mimic the in vivo conditions of a tumor's space-constrained growth in 3-D environments in contrast to traditionally used culture flasks.

    Surprisingly, the team observed that such confinement resulted in the abnormal division of a single cancer cell into three or four daughter cells at a much higher rate than typical. And a few times, they observed a single cell splitting into five daughter cells during a single division event, likely leading to aneuploid daughter cells.

    "Even though cancer can arise from a set of precise mutations, the majority of malignant tumors possess aneuploid cells, and the reason for this is still an open question," said Di Carlo, who is also a member of the California NanoSystems Institute at UCLA. "Our new microfluidic platform offers a more reliable way for researchers to study how the unique tumor environment may contribute to aneuploidy."

    ###

    Other authors on the paper included Henry Tat Kwong Tse and Westbrook McConnell Weaver, both UCLA biomedical engineering graduate students. The research team is currently seeking to partner with cancer researchers to further investigate the importance of confined environments on the development of cancer.

    The study was funded by the UCLA Henry Samueli School of Engineering and Applied Science.

    For more on the Di Carlo laboratory's research, visit www.biomicrofluidics.com.

    The UCLA Henry Samueli School of Engineering and Applied Science, established in 1945, offers 28 academic and professional degree programs and has an enrollment of more than 5,000 students. The school's distinguished faculty are leading research to address many of the critical challenges of the 21st century, including renewable energy, clean water, health care, wireless sensing and networking, and cybersecurity. Ranked among the top 10 engineering schools at public universities nationwide, the school is home to nine multimillion-dollar interdisciplinary research centers in wireless sensor systems, wireless health, nanoelectronics, nanomedicine, renewable energy, customized computing, the smart grid, and the Internet, all funded by federal and private agencies and individual donors.


    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


    Source: http://www.eurekalert.org/pub_releases/2012-07/uoc--ubd070512.php

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    Jennifer Aniston REJECTS Justin Theroux Marriage Proposal ... According to Tabloid


    Did Jennifer Aniston recently shoot down a marriage proposal from Justin Theroux?

    According to OK! Magazine, she did!!! So no, there's no way in hell that occurred.

    The publication claims that her actor beau FINALLY proposed (they've been dating like 14 whole months now), but that he got nixed when he did.

    What could this "engagement shocker" entail?

    Aniston Proposal

    Apparently there was also:

    • A fight over her ring.
    • A major blunder on his part.
    • Unexpected advice from Brad Pitt to Jen.

    What could that entail? Since this story is, you know, fake ... our guess is that there was no ring, no proposal, no rejection, no shocker and no advice, and that Jennifer Aniston and Justin Theroux are just happy being a couple for now.

    Source: http://www.thehollywoodgossip.com/2012/07/jennifer-aniston-rejects-justin-theroux-marriage-proposal-accord/

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    Wednesday, July 4, 2012

    Organic tomatoes contain higher levels of antioxidants than conventional tomatoes, study suggests

    ScienceDaily (July 3, 2012) ? A study conducted at the University of Barcelona shows that organic tomatoes contain higher levels of phenolic compounds than conventional tomatoes. Phenolic compounds are organic molecules found in many vegetables with proven human health benefits. The UB's Natural Antioxidant Group, headed by lecturer Rosa M. Lamuela, had previously demonstrated that organic tomato juice and ketchup contain higher polyphenol content than juice and ketchup made from conventionally grown tomatoes.

    Lamuela points out that during the production process of ketchup and juice, there are lower levels of polyphenols; therefore it was necessary to verify that the differences observed in previous studies had their origin in the tomatoes themselves and not in the technology used during the production process. As lecturer Lamuela states, "it must be verified with raw material."

    Polyphenols -- natural antioxidants of plant origin -- are considered to be of great nutritional interest because its consumption is associated with reduced risk of cardiovascular and degenerative diseases, and some forms of cancer. The team behind the study has analyzed a variety of tomato called Daniela and has determined its phenolic profile by using liquid chromatography coupled to mass spectrometry. With this method, the research group of the UB could identify 34 different phenolic compounds in tomatoes. According to Rosa M. Lamuela, "the benefit of taking polyphenols through foods is that they contain a wide variety of such molecules, which are increased." This would be more beneficial to health than the intake of supplements. Tomatoes also contain lycopene and other carotenoids, and vitamin C. Hence, according to Lamuela, "they contain many beneficial compounds."

    Organic or conventional crops?

    Differences between organic and conventional tomatoes can be explained by the manure used in both cases. "Organic farming doesn't use nitrogenous fertilizers; as a result, plants respond by activating their own defense mechanisms, increasing the levels of all antioxidants," explains the first author of the article, Anna Vallverd? Queralt. "The more stress plants suffer, the more polyphenols they produce," points out lecturer Lamuela. Numerous scientific investigations show that the consumption of these antioxidants has numerous health benefits. Researchers claim that more studies of clinical evidence are still needed to be able to state that organic products are truly better for our health than conventional ones. Lamuela would like to carry out a study with humans comparing organic and conventional tomato consumers.

    Also participating in this research, published in the Journal of Agricultural and Food Chemistry, are researchers Olga Ja?uregui, from the UB's Scientific and Technological Centres (CCiTUB), and Alexander Medina Remo?n, who, together with Rosa M. Lamuela and Anna Vallverd? Queralt, are from the UB's Department of Nutrition and Bromatology, from the Reference Network on Food Technology of the Government of Catalonia (XaRTA) and from the Institute for Research on Nutrition and Food Safety (INSA-UB). This research group is also affiliated to the Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (CIBERobn) and RETICS networks, from Carlos III Health Institute.

    Share this story on Facebook, Twitter, and Google:

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    Story Source:

    The above story is reprinted from materials provided by Universidad de Barcelona, via AlphaGalileo.

    Note: Materials may be edited for content and length. For further information, please contact the source cited above.


    Journal Reference:

    1. Anna Vallverd?-Queralt, Olga J?uregui, Alexander Medina-Rem?n, Rosa Maria Lamuela-Ravent?s. Evaluation of a Method To Characterize the Phenolic Profile of Organic and Conventional Tomatoes. Journal of Agricultural and Food Chemistry, 2012; 60 (13): 3373 DOI: 10.1021/jf204702f

    Note: If no author is given, the source is cited instead.

    Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

    Source: http://www.sciencedaily.com/releases/2012/07/120703120630.htm

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    How to restore your address book after Facebook messed it up

    18 hrs.

    Recently, Facebook changed everyone's email to an @facebook.com address. Even if you fixed the problem, you may find that Facebook changed all of the contacts in your phone, too. Here's how to fix it.

    A lot of us sync our Facebook accounts with our address books on our smartphones, so we always have up-to-date phone numbers, email addresses, and pictures for all of our friends. However, with Facebook changing everyone's email to @facebook.com last week, blogger Rachel Luxemburg (and a lot of other people) found that those changes were synced down to their phone?meaning they don't have any of their friends' actual email addresses anymore. Just the facebook.com ones.

    None of us at Lifehacker have noticed this problem, but we do have a few ideas about how to fix it. In fact, this will fix any similar problem you have where your contacts get messed up. Here's what you need to do.

    Step one: Restore your contacts to a previous state
    Some services?particularly Google?regularly back up your contacts so if something goes wrong, you can restore them. And, since nearly all Android users sync their contacts with Google?as well as many iPhone users?this is a good way to fix the contacts on your phone. To do so, just follow these instructions:

    1. Before you do anything else, go to your phone and turn off Facebook syncing for your contact list. On Android, this is in the Facebook app under Settings > Sync Contacts. Just set it to "Don't Sync". On the iPhone, go to the Facebook app, click the menu button, scroll down to "Friends", then hit the share button in the upper right-hand corner. Tap "Sync Contacts" and turn syncing off. Note that depending on your platform, you may have a "Remove Facebook Data" button on the contact syncing screen?tapping this will also turn off syncing.
    2. Go to your Gmail inbox, and click on the "Gmail" label under the Google logo. Go to Contacts. Remember, this trick only works if you were syncing your phone with your Google contacts.
    3. Click the "More" button and go to "Restore Contacts". We don't know exactly when the Facebook change happened, but you'll probably want to set it to restore your contacts from a day before June 22, 2012, so set it to whatever you need to go back that far.
    4. Click the Restore button. When it finishes, you should hopefully find that all of your contacts' correct email addresses have been restored! As long as you don't sync with Facebook again, they should stay that way.

    If you don't sync your contacts with Google, check to see if your desktop address book has any alternatives. For example, if you're on a Mac and you back it up with Time Machine, you can just open up Address Book, invoke Time Machine from the menu bar, then restore it to a date before the Facebook ridiculousness happened. Then when you re-sync your iPhone, you should be good to go. Check your address book app's documentation for more info on whether it has an automatic backup feature.

    Step two: Remind your friends to change their Facebook profile
    If you can't restore your address book?or if you still want to be able to sync your Facebook?the only thing you can do is get all your friends to change their Facebook profile back to the way it was. That way, Facebook will sync their correct email address back to your phone. We've shown you how to do this before, so if you haven't already, spread the word to all your friends and family so they don't run into problems later on.

    We couldn't test these instructions ourselves, because none of us have experienced the issue, but this should help you get your contacts back to the way they were (or at least closer). If you'ved this issue, let us know how these instructions work for you in the comments below.

    More from Lifehacker:



    Source: http://www.technolog.msnbc.msn.com/technology/technolog/how-restore-your-address-book-after-facebook-messed-it-860566

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